\BOOKMARK [1][-]{section.1}{Availability}{}% 1 \BOOKMARK [1][-]{section.2}{Authors}{}% 2 \BOOKMARK [1][-]{section.3}{Overview}{}% 3 \BOOKMARK [1][-]{section.4}{Bug report}{}% 4 \BOOKMARK [1][-]{section.5}{Installing PhyML}{}% 5 \BOOKMARK [2][-]{subsection.5.1}{Sources and compilation}{section.5}% 6 \BOOKMARK [2][-]{subsection.5.2}{Installing PhyML on UNIX-like systems \(including Mac OS\)}{section.5}% 7 \BOOKMARK [2][-]{subsection.5.3}{Installing PhyML on Microsoft Windows}{section.5}% 8 \BOOKMARK [2][-]{subsection.5.4}{Installing the parallel version of PhyML}{section.5}% 9 \BOOKMARK [1][-]{section.6}{Program usage.}{}% 10 \BOOKMARK [2][-]{subsection.6.1}{PHYLIP-like interface}{section.6}% 11 \BOOKMARK [3][-]{subsubsection.6.1.1}{Input Data sub-menu}{subsection.6.1}% 12 \BOOKMARK [3][-]{subsubsection.6.1.2}{Substitution model sub-menu}{subsection.6.1}% 13 \BOOKMARK [3][-]{subsubsection.6.1.3}{Tree searching sub-menu}{subsection.6.1}% 14 \BOOKMARK [3][-]{subsubsection.6.1.4}{Branch support sub-menu}{subsection.6.1}% 15 \BOOKMARK [2][-]{subsection.6.2}{Command-line interface}{section.6}% 16 \BOOKMARK [2][-]{subsection.6.3}{XML interface}{section.6}% 17 \BOOKMARK [2][-]{subsection.6.4}{Parallel bootstrap}{section.6}% 18 \BOOKMARK [1][-]{section.7}{Inputs \046 outputs for command-line and PHYLIP interface }{}% 19 \BOOKMARK [2][-]{subsection.7.1}{Sequence formats}{section.7}% 20 \BOOKMARK [3][-]{subsubsection.7.1.1}{Gaps and ambiguous characters}{subsection.7.1}% 21 \BOOKMARK [3][-]{subsubsection.7.1.2}{Specifying outgroup sequences}{subsection.7.1}% 22 \BOOKMARK [2][-]{subsection.7.2}{Tree format}{section.7}% 23 \BOOKMARK [2][-]{subsection.7.3}{Multiple alignments and trees}{section.7}% 24 \BOOKMARK [2][-]{subsection.7.4}{Custom amino-acid rate model}{section.7}% 25 \BOOKMARK [2][-]{subsection.7.5}{Topological constraint file}{section.7}% 26 \BOOKMARK [2][-]{subsection.7.6}{Output files}{section.7}% 27 \BOOKMARK [2][-]{subsection.7.7}{Treatment of invariable sites with fixed branch lengths}{section.7}% 28 \BOOKMARK [1][-]{section.8}{Inputs \046 outputs for the XML interface }{}% 29 \BOOKMARK [2][-]{subsection.8.1}{Mixture models in PhyML}{section.8}% 30 \BOOKMARK [2][-]{subsection.8.2}{Partitions}{section.8}% 31 \BOOKMARK [2][-]{subsection.8.3}{Combining mixture and partitions in PhyML: the theory}{section.8}% 32 \BOOKMARK [2][-]{subsection.8.4}{The XML format and its use in PhyML}{section.8}% 33 \BOOKMARK [2][-]{subsection.8.5}{Setting up mixture and partition models in PhyML: the basics}{section.8}% 34 \BOOKMARK [2][-]{subsection.8.6}{XML options}{section.8}% 35 \BOOKMARK [3][-]{subsubsection.8.6.1}{phyml component}{subsection.8.6}% 36 \BOOKMARK [3][-]{subsubsection.8.6.2}{topology component}{subsection.8.6}% 37 \BOOKMARK [3][-]{subsubsection.8.6.3}{ratematrices component}{subsection.8.6}% 38 \BOOKMARK [3][-]{subsubsection.8.6.4}{equfreqs component}{subsection.8.6}% 39 \BOOKMARK [3][-]{subsubsection.8.6.5}{branchlengths component}{subsection.8.6}% 40 \BOOKMARK [3][-]{subsubsection.8.6.6}{siterates component}{subsection.8.6}% 41 \BOOKMARK [3][-]{subsubsection.8.6.7}{partitionelem and mixtureelem components}{subsection.8.6}% 42 \BOOKMARK [2][-]{subsection.8.7}{A simple example: GTR + 4 + I}{section.8}% 43 \BOOKMARK [2][-]{subsection.8.8}{A second example: LG4X}{section.8}% 44 \BOOKMARK [2][-]{subsection.8.9}{An example with multiple partition elements}{section.8}% 45 \BOOKMARK [2][-]{subsection.8.10}{Branch lengths with invariants and partionned data}{section.8}% 46 \BOOKMARK [1][-]{section.9}{Citing PhyML}{}% 47 \BOOKMARK [1][-]{section.10}{Other programs in the PhyML package}{}% 48 \BOOKMARK [2][-]{subsection.10.1}{PhyTime}{section.10}% 49 \BOOKMARK [3][-]{subsubsection.10.1.1}{Installing PhyTime}{subsection.10.1}% 50 \BOOKMARK [3][-]{subsubsection.10.1.2}{Running PhyTime}{subsection.10.1}% 51 \BOOKMARK [3][-]{subsubsection.10.1.3}{Upper bounds of model parameters}{subsection.10.1}% 52 \BOOKMARK [3][-]{subsubsection.10.1.4}{PhyTime specific options}{subsection.10.1}% 53 \BOOKMARK [3][-]{subsubsection.10.1.5}{PhyTime output}{subsection.10.1}% 54 \BOOKMARK [3][-]{subsubsection.10.1.6}{ClockRate vs. EvolRate}{subsection.10.1}% 55 \BOOKMARK [3][-]{subsubsection.10.1.7}{Effective sample size}{subsection.10.1}% 56 \BOOKMARK [3][-]{subsubsection.10.1.8}{Prior distributions of model parameters}{subsection.10.1}% 57 \BOOKMARK [3][-]{subsubsection.10.1.9}{Citing PhyTime}{subsection.10.1}% 58 \BOOKMARK [1][-]{section.11}{Recommendations on program usage}{}% 59 \BOOKMARK [2][-]{subsection.11.1}{PhyML}{section.11}% 60 \BOOKMARK [2][-]{subsection.11.2}{PhyTime}{section.11}% 61 \BOOKMARK [1][-]{section.12}{Frequently asked questions}{}% 62 \BOOKMARK [1][-]{section.13}{Acknowledgements}{}% 63