#Please insert up references in the next lines (line starts with keyword UP) UP arb.hlp UP glossary.hlp UP arb_edit4.hlp #Please insert subtopic references (line starts with keyword SUB) #SUB subtopic.hlp SUB pt_server.hlp # Hypertext links in helptext can be added like this: LINK{ref.hlp|http://add|bla@domain} #************* Title of helpfile !! and start of real helpfile ******** TITLE Old aligner from ARB_EDIT OCCURRENCE ARB_EDIT4/Edit/Old aligner from ARB_EDIT DESCRIPTION Aligns or realigns selected sequence with the database sequences. The most similar database sequences are found, and the new sequence is aligned with these according to primary and secondary structure similarity. Select whether to align the sequence of the selected species or all marked species. Select whether to align versus an explicit reference or the nearest relative reported by the PT_SERVER. The used relatives may be marked by checking 'Mark sequences found by the pt_server'. Press NOTES Marking the closest relatives allows manual optimization of the alignment of the new species with its closest relatives. EXAMPLES None WARNINGS The aligner version available with the present package often does not properly align short partial sequences. BUGS The aligner needs lots of computer memory, sometimes more than you have. In this case it may not align some sequences. The aligner does not align the last 3-6 bases of short sequences correctly. Look at the end of your sequences.