Restriction sites will accept a file of restriction enzymes, and will locate all occurences in the selected sequences. The format of the file is single line entries with the recognition site followed by the enzyme name. For example: TTCGAA AcpI WCCGGW BcaI TCCGGA BspEI For the most complete set of current restriction enzymes, Dr. Richard J. Roberts' REBASE database is available via anonymous ftp from rna.cshl.org. This list is updated frequently, and includes information about methylation sites, isoschizomers, references, and commercial sources.